Parkinson's DiseaseAbout This Hardback Parkinson's disease (PD) is a degenerative disorder of the central nervous system, which affects the motor system. In PD, a progressive cell death in the basal ganglia of the brain affects the dopamine secreting neurons present in the substantia nigra pars compacta. This impacts the functioning of the motor, oculo motor, limbic, associative and orbitofrontal circuits of the brain. As the disease progresses, non motor functions are
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